Drug Points: Metabolic abnormality induced by streptomycin
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منابع مشابه
Drug Points Depression induced by etretinate
Drs C A HENDERSON and A S HIGHET (York District Hospital, York Y03 7HE) write: We report three cases of depression associated with etretinate treatment. In 1984 a 49 year old, 90 kg man with plaque psoriasis started taking etretinate 100 mg/day. Despite a reduction in dose the drug had to be discontinued owing to peeling skin, thinning hair, and depression. These effects resolved a few weeks la...
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Various degrees of gingival overgrowth may occur in individuals taking diphenylhydantoin, a drug used widely in the treatment of epilepsy. The tissue overgrowth is made up predominantly of collagen, and may therefore be a useful model for analysis of fibrosis and some other connective tissue abnormalities. Fibroblasts derived from the overgrown tissue exhibit a level of protein synthetic activi...
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The aim of this study was to determine the association of n-acetyltransferase-2 polymorphisms and anti-tuberculosis drug-induced hepatotoxicity in Iranian pulmonary tuberculosis patients. Acetylating phenotypes was studied in 50 Iranian pulmonary tuberculosis patients using metabolic ratio of plasma acetyl-Isoniazid to Isoniazid. The association between hepatotoxicity and the n-acetyltransferas...
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The aim of this study was to determine the association of n-acetyltransferase-2 polymorphisms and anti-tuberculosis drug-induced hepatotoxicity in Iranian pulmonary tuberculosis patients. Acetylating phenotypes was studied in 50 Iranian pulmonary tuberculosis patients using metabolic ratio of plasma acetyl-Isoniazid to Isoniazid. The association between hepatotoxicity and the n-acetyltransferas...
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ژورنال
عنوان ژورنال: BMJ
سال: 1994
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.309.6953.512